Science

Hyaluronic Acid

Deeply hydrates and supports the skin barrier – In a randomized, double-blind trial of 129 healthy women aged 18–65, only 100mg of oral hyaluronic acid significantly improved skin hydration within 2 - 8 weeks and increased epidermal thickness after 12 weeks across both young and older participants. (Gao et al.,  2023)

Relieves dryness fast – In a placebo-controlled study, 240 mg/day of oral hyaluronic acid improved skin dryness on the face and body in just 3 weeks, with increased moisture under the eyes continuing through week 6. (Kajimoto et al., 2001)

Visibly reduces wrinkles and water loss – In a placebo-controlled trial of adults aged 35–64, 120 mg/day of hyaluronic acid significantly improved wrinkle appearance by week 8 and reduced transepidermal water loss (TEWL) after 8 weeks. (Hsu et al., 2021)

Ceramides

Boosts moisture and fortifies your skin barrier – In a double-blind, placebo-controlled trial of adults aged 21 – 45, just 0.6 mg/day of rice-derived glucosylceramides for 4 weeks significantly increased skin hydration and reduced transepidermal water loss on the cheek and arm versus placebo. (Takahashi et al., 2023)

Improves Lip Moisture and Pore Visibility — In a 12 week study with Orzya Ceramide® dosed at 1.2mg of GlcCer (we use 10mg) and 40 µg β‑sitosterol glucoside (a naturally occurring compound in rice) significantly reduced cheek TEWL, improved lip moisture, and reduced the number of visible pores. (Takara et al., 2021)

Increases Firmness and Elasticity and Improves Wrinkles — In a prospective, open label study featuring 40mg of KOMCERA® Rice Ceramides taken daily, firmness, elasticity, and wrinkle markers were all significantly improved by the end of the 12 week trial. (Leo et al., 2022)

We use 100 mg of rice‑derived ceramides standardized to 10 mg glucosylceramide (GlcCer). Forms and delivery systems vary across studies; taken together, clinical and mechanistic evidence supports hydration, barrier, and wrinkle‑appearance benefits that complement HA and MSM.

MSM (Methylsulfonylmethane)

Brighter, smoother, more hydrated skin, fast – In a 16-week study, 1 g/day of OptiMSM® gave people 9.5% more facial radiance by week 4 and 21.8% by week 16. The same dose cut skin roughness by 10.3% at week 4 and 22.6% at week 16, and boosted skin moisture by 4.3% at week 4 and 22.5% at week 16, showing a robust reduction in skin ageing (Muizzuddin et al., 2020)

We use 99.9%-pure MSM (non-OptiMSM®) at the same 1/g per day dose shown to give your skin the support it needs to be its best.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Results, times, and magnitudes vary by individual, dose, and formulation.